Research Assistant I - Mass Spectrometry
Baylor College of Medicine
Houston, TX
Job posting number: #7295949 (Ref:20984-en_US)
Posted: December 12, 2024
Job Description
Summary
Dr. Putluri's lab at Baylor College of Medicine is seeking a highly motivated Research Assistant with expertise in massspectrometry to join our interdisciplinary team. This position focuses on applying advanced mass spectrometrytechniques in metabolomics and cancer /non-cancer metabolism. The successful candidate will be involved indeveloping and optimizing mass spectrometry-based methods to support ongoing research projects
Job Duties
- Perform routine molecular biology techniques such as PCR, qPCR, Western blotting, DNA/RNA extraction, gel electrophoresis, and cloning.
- Conduct cell culture, transfections, and viral transductions as needed.
- Perform daily monitoring and care of laboratory mice, including feeding, general health assessments, and record-keeping.
- Assist in next-generation sequencing (NGS) library preparation or other advanced genomic techniques. Assist with or perform in vivo experiments, such as administering compounds via various routes (e.g., oral gavage, intraperitoneal or subcutaneous injections).
- Collect tissue samples, blood, or other biological materials from mice for downstream molecular biology analyses (e.g., tumor tissue for metabolomics or genetic studies).
- Utilize software for data analysis, such as Excel, R, or Python, and maintain accurate records in laboratory notebooks or electronic systems.
- Develop and execute cutting-edge mass spectrometry workflows for targeted and untargeted metabolomics, lipidomics, and fluxomics studies.
- Perform high-resolution mass spectrometry experiments using Orbitrap, QTRAP, or triple quadrupole instruments.
- Assist with experimental design for collaborative projects. Candidates need to work with Lab Directors, Junior faculties, and postdoc.
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Stay updated on advancements in mass spectrometry and implement new techniques to enhance laboratory capabilities.
Minimum Qualifications
- Bachelor's degree in a Basic Science or a related field.
- Two years of relevant experience.
Preferred Qualifications
- Master's degree in basic science or a related field with experience in analytical chemistry, chemistry, biochemistry, cancer biology, or a related field.
- In depth knowledge of mass spectrometry instrumentation, such as Orbitrap or QTRAP, and liquidchromatography (LC-MS/MS) or gas chromatography (GC-MS) techniques.
- Strong background in metabolomics, lipidomics, or fluxomics, with demonstrated expertise in data analysis andinterpretation.
- Proficiency in data analysis software (e.g., Xcalibur, Analyst, Compound Discoverer, MetaboAnalyst).
- Excellent communication skills and a strong track record of publications.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.
